• Patients who have the highest risk for multiple pregnancy, such as those women who are young (less than 35) and those receiving eggs from a young donor.
• A couple who produces a large number of embryos.
• Any couple who cannot risk the chance of a having triplets or higher order pregnancy, regardless of the reason.
• Those for whom Selective Pregnancy Reduction is not an option.

In all cases, we do not culture embryos to the Blastocyst stage unless there are at least two or three good quality 8-cell embryos when the embryos are evaluated on day three.