Assisted reproductive technologies (ART) include In Vitro Fertilization (IVF) which is the technique of fertilizing a woman's eggs in the laboratory for the treatment of Infertility. While it was designed originally for women with tubal disease, IVF has been extended with equal success to Infertility due to Endometriosis, poor cervical mucus and unexplained factors. A variant of IVF, the GIFT procedure is available to women with normal fallopian tubes. IVF has also been applied to male factor Infertility. While the success rates of standard ART in these cases used to be low, the recent advances in assisted fertilization through ICSI can succeed even in couples with severe sperm abnormalities. ART attempts using the woman's own eggs drastically drop above the age of 43 years. Fortunately, pregnancy initiation with donor oocytes has proven highly effective in women who are no longer good candidates for traditional ART as well as women with non-functioning ovaries.